Search results for " Dyslexia"

showing 10 items of 60 documents

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia

2019

Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high impact on school and psychosocial development and high comorbidity with conditions like attention-deficit hyperactivity disorder (ADHD), depression, and anxiety. DD is characterized by deficits in different cognitive skills, including word reading, spelling, rapid naming, and phonology. To investigate the genetic basis of DD, we conducted a genome-wide association study (GWAS) of these skills within one of the largest studies available, including nine cohorts of reading-impaired and typically developing children of European ancestry (N = 2562–3468). We observed a genome-wide significant effect (p < 1 × 10…

0301 basic medicineMaleCandidate geneMultifactorial InheritanceImaging geneticsQH301 BiologyLANGUAGEGenome-wide association study3124 Neurology and psychiatryCANDIDATE GENESDyslexiaCohort StudiesREADING-DISABILITYMOLECULAR-GENETICS0302 clinical medicineCognitionAUTOMATIZED NAMING RANChildSUSCEPTIBILITY LOCUSRapid automatized namingR2CSHORT-TERM-MEMORY~DC~IMAGING-GENETICSRJ Pediatrics[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesPsychiatry and Mental healthDyslexia/geneticsAnxietyFemalemedicine.symptomBDCRC0321 Neuroscience. Biological psychiatry. NeuropsychiatryClinical psychologyNeuroinformaticsAdultReading disabilityAdolescentGenotypeRJPolymorphism Single NucleotideArticlelcsh:RC321-571ENVIRONMENTAL-INFLUENCES03 medical and health sciencesCellular and Molecular NeuroscienceQH301Young AdultmedicinedysleksiaHumansGenetic Predisposition to Diseaselcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological Psychiatrygeenitbusiness.industryDyslexiaDASmedicine.diseaseComorbiditypredictors030104 developmental biology[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsRC0321DEVELOPMENTAL DYSLEXIAbusiness030217 neurology & neurosurgeryGenome-Wide Association Study
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An extensive pattern of atypical neural speech-sound discrimination in newborns at risk of dyslexia.

2019

Objective: Identifying early signs of developmental dyslexia, associated with deficient speech-sound processing, is paramount to establish early interventions. We aimed to find early speech-sound processing deficiencies in dyslexia, expecting diminished and atypically lateralized event-related potentials (ERP) and mismatch responses (MMR) in newborns at dyslexia risk. Methods: ERPs were recorded to a pseudoword and its variants (vowel-duration, vowel-identity, and syllable-frequency changes) from 88 newborns at high or no familial risk. The response significance was tested, and group, laterality, and frontality effects were assessed with repeated-measures ANOVA. Results: An early positive a…

6162 Cognitive scienceMaleSpeech soundAudiologyEvent-related potential (ERP)Dyslexia0302 clinical medicineEARLY LANGUAGE-ACQUISITIONnewbornMedicineFAMILIAL RISKAuditoryBRAIN RESPONSES05 social sciencesevent-related potential (ERP)ElectroencephalographySensory SystemsLanguage developmentNeurologyLateralityEvoked Potentials AuditorySpeech PerceptionFemaleAnalysis of variancespeech soundpsychological phenomena and processesmedicine.medical_specialty515 PsychologyMISMATCH NEGATIVITY MMNCORTICAL RESPONSESEVENT-RELATED POTENTIALSGENETIC RISKbehavioral disciplines and activities050105 experimental psychology03 medical and health sciencesSpeech discriminationEvent-related potentialPhoneticsPhysiology (medical)Vowelotorhinolaryngologic diseasesdysleksiaHumansSpeech0501 psychology and cognitive sciencesauditoryAUDITORY-DISCRIMINATIONMismatch response (MMR)vastasyntyneetAuditory Cortexbusiness.industrypuheääni3112 NeurosciencesDyslexiaInfant NewbornNewbornmismatch response (MMR)medicine.diseaseta3124PseudowordPHONEME MISMATCHAcoustic StimulationDEVELOPMENTAL DYSLEXIANeurology (clinical)business030217 neurology & neurosurgeryClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Ability for Voice Recognition Is a Marker for Dyslexia in Children

2014

A recent voice recognition experiment conducted by Perrachione, Del Tufo, and Gabrieli (2011) revealed that, in normal adult readers, the accuracy at identifying human voices was better in the participants’ mother tongue than in an unfamiliar language, while this difference was absent in a group of adults with dyslexia. This pattern favored a view of dyslexia as due to “fundamentally impoverished native-language phonological representations.” To further examine this issue, we conducted two voice recognition experiments, one with children with/without dyslexia, and the other with adults with/without dyslexia. Results revealed that children/adults with dyslexia were less accurate at identify…

AdultMaleAdolescentSpeech recognitionFirst languageExperimental and Cognitive PsychologyPhonological deficitBiological theories of dyslexiaDevelopmental psychologyDyslexiaYoung AdultArts and Humanities (miscellaneous)PhoneticsmedicineHumansChildGeneral PsychologyLanguageDyslexiaMultisensory integrationRecognition PsychologyGeneral Medicinemedicine.diseaseVoiceFemalemedicine.symptomPsychologySurface dyslexiaCognitive psychologyExperimental Psychology
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How to improve reading skills in dyslexics: the effect of high frequency rTMS.

2013

The latest progress in understanding remediation of dyslexia underlines how some changes in brain are a necessary mechanism of improvement. We wanted to determine whether high frequency repetitive transcranial magnetic stimulation (hf-rTMS) over areas that are underactive during reading in dyslexics, would improve reading of dyslexic adults. We applied 5Hz-TMS over both left and right inferior parietal lobule (IPL) and superior temporal gyrus (STG) prior to word, non-word and text reading aloud. Results show that hf-rTMS stimulation over the left IPL improves non-word reading accuracy and hf-rTMS stimulation over the left STG increases word reading speed and text reading accuracy. Moreover …

AdultMaleCognitive Neurosciencemedicine.medical_treatmentmedia_common.quotation_subjectExperimental and Cognitive Psychologybehavioral disciplines and activitiesVocabularyFunctional LateralityTranscranial magnetic stimulation; Superior temporal gyrus; Inferior parietal lobe; DyslexiaDyslexiaBehavioral NeuroscienceSuperior temporal gyrusYoung AdultReading (process)Parietal LobemedicineReaction TimeHumansmedia_commonWord readingAnalysis of VarianceSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaSuperior temporal gyrusBRAIN STIMULATIONDyslexiaInferior parietal lobuleMiddle Agedmedicine.diseaseTranscranial Magnetic StimulationTemporal LobeTranscranial magnetic stimulationReadingFacilitationSettore MED/26 - NeurologiaFemalesense organsPsychologyInferior parietal lobeReading skillsPhotic StimulationCognitive psychologyNeuropsychologia
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Late-Emerging and Resolving Dyslexia

2015

This study focuses on the stability of dyslexia status from Grade 2 to Grade 8 in four groups: (a) no dyslexia in either grade (no-dyslexia, n = 127); (b) no dyslexia in Grade 2 but dyslexia in Grade 8 (late-emerging, n = 18); (c) dyslexia in Grade 2 but not in Grade 8 (resolving, n = 15); and (d) dyslexia in both grades (persistent-dyslexia, n = 22). We examined group differences from age 3.5 to age 14 in (a) reading, vocabulary, phonology, letter knowledge, rapid naming, IQ, verbal memory; (b) familial and environmental risk and supportive factors; and (c) parental skills in reading, phonology, rapid naming, verbal memory, and vocabulary. Our findings showed group differences both in read…

AdultMaleParentsRiskVocabularyAdolescentmedia_common.quotation_subjectbehavioral disciplines and activitiesDevelopmental psychologyDyslexiaChild DevelopmentLate-emerging dyslexiaReading (process)mental disordersDevelopmental and Educational PsychologymedicineHumansdysleksiaCognitive skillAge of OnsetChildmedia_commonLanguage TestsFamily risk for dyslexiaDyslexiaCognitionPhonologyPrognosis/dk/atira/pure/sustainabledevelopmentgoals/quality_educationmedicine.diseasenervous system diseasesPsychiatry and Mental healthEarly identificationChild PreschoolDisease ProgressionFemaleDisease SusceptibilityReading disabilitiesVerbal memoryAge of onsetPsychologySDG 4 - Quality EducationFollow-Up StudiesJournal of Abnormal Child Psychology
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Does viotin activate violin more than viocin? On the use of visual cues during visual-word recognition.

2013

The vast majority of neural and computational models of visual-word recognition assume that lexical access is achieved via the activation of abstract letter identities. Thus, a word’s overall shape should play no role in this process. In the present lexical decision experiment, we compared word-like pseudowords like viotín (same shape as its base word: violín) vs. viocín (different shape) in mature (college-aged skilled readers), immature (normally reading children), and immature/impaired (young readers with developmental dyslexia) word-recognition systems. Results revealed similar response times (and error rates) to consistent-shape and inconsistent-shape pseudowords for both adult skille…

AdultMalemedia_common.quotation_subjectDecision MakingExperimental and Cognitive PsychologyViolinDyslexiaYoung AdultArts and Humanities (miscellaneous)Reading (process)Lexical decision taskmedicineReaction TimeContrast (vision)HumansChildSensory cueGeneral Psychologymedia_commonVisual word recognitionAnalysis of VarianceDyslexiaGeneral Medicinemedicine.diseaseLinguisticsPattern Recognition VisualReadingDevelopmental dyslexiaFemaleCuesPsychologyCognitive psychologyExperimental psychology
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Developmental dyslexia: re-evaluation of the corpus callosum in male adults.

2000

Using a new method based upon the measurement of four angles, we analyzed the corpus callosum of 23 adult male dyslexics and 25 age-matched controls on MRI sagittal scans. Two out of the four angles measured showed significant differences between the groups that are consistent with previous findings concerning the size of the corpus callosum in dyslexics. In particular, posterior regions are concerned, displaying a lowered corpus callosum in dyslexics. These findings are discussed in relation to cortical parietal asymmetries and possible hormonal events, referring to the testosterone hypothesis, that could occur in utero or in the perinatal period in the dyslexic population.

AdultMalemedicine.medical_specialtyAdult malePopulationAudiologyCorpus callosumCorpus CallosumDyslexiaReference ValuesmedicineHumanseducationeducation.field_of_studymedicine.diagnostic_testbusiness.industryMagnetic resonance imagingMagnetic Resonance ImagingSagittal planemedicine.anatomical_structureNeurologyIn uteroDevelopmental dyslexiaNeurology (clinical)businessNeurosciencePerinatal periodEuropean neurology
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Maternal stress and coping strategies in developmental Dyslexia: An Italian multicenter study

2017

BackgroundStudies about the impact of developmental dyslexia (DD) on parenting are scarce. Our investigation aimed to assess maternal stress levels and mothers’ copying styles in a population of dyslexic children.MethodsA total of 874 children (500 boys, 374 girls; mean age 8.32 ± 2.33 years) affected by DD was included in the study. A total of 1,421 typically developing children (789 boys, 632 girls; mean age 8.25 ± 3.19 years) were recruited from local schools of participating Italian Regions (Abruzzo, Calabria, Campania, Puglia, Umbria, Sicily) and used as control-children group. All mothers (of both DD and typically developing children) filled out an evaluation for parental stress (Pare…

Coping (psychology)lcsh:RC435-571Developmental dyslexiaPopulationDysfunctional familyChildren; Coping strategies; Developmental dyslexia; Maternal emotions; Parental stress;Children; Coping strategies; Developmental dyslexia; Maternal emotions; Parental stress; Psychiatry and Mental Health03 medical and health sciencesMaternal stressCoping strategieSettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'Educazione0302 clinical medicinelcsh:PsychiatryMaternal emotionsMedicineClinical significanceParental stresseducationChildren; Coping strategies; Developmental dyslexia; Maternal emotions; Parental stressChildrenOriginal ResearchPsychiatryCoping strategieseducation.field_of_studybusiness.industry05 social sciences050301 educationSettore MED/39 - Neuropsichiatria InfantileMulticenter studyParental strePsychiatry and Mental HealthDevelopmental dyslexiaParental stressMaternal emotionbusiness0503 education030217 neurology & neurosurgeryClinical psychology
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CORRELATION AMONG DYSLEXIA, DYSPRAXIA AND DYSCALCULIA IN STUDENTS WITH LEARNING DYSABILITIES

2016

The article is devoted to evaluate the correlation among dyslexia, dyspraxia and dyscalculia in students with learning dysabilities. There is a point of view that students with learning dysabilities mostly have dyspraxia, but not all of them have dyscalculia or dyslexia. There is a necessity to have theoretical findings and state criteria for evaluation to carry out empirical research. Students with learning dysabilities have difficulties in many areas, but it is not possible to assure that all of them meet the same problems.

CorrelationEmpirical researchdyscalculia; dyslexia; dyspraxia; learning dysabilitiesDyscalculiamedicineDyslexiaPsychologymedicine.diseaseCognitive psychologySOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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Il ruolo dell'informazione contestuale e delle componenti sillabico-accentuali nella decodifica del testo scritto: un confronto tra dislessici evolut…

2010

L'esperimento qui presentato si propone di valutare l'importanza che assume, per un dislessico evolutivo rispetto ad un normolettore, la presenza di indizi che suggeriscano il significato del testo scritto (informazioni contestuali), nonché l'influenza di determinate caratteristiche sillabico-accentuali nelle prestazioni di lettura. Lo studio è stato condotto attraverso la somministrazione di frasi in ognuna delle quali è stata inserita una parola target secondo criteri relativi alla posizione (dislocazione a sinistra e dislocazione a destra) al fine di valutare l'influenza esercitata dall'informazione contestuale durante la decifrazione del testo. Le parole selezionate sono state accuratam…

Developmental dyslexia stress assignment syllabic structure contextual facilitation semantic cuesInformazione contestualeDislessia
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